Synthesis and biological evaluation of novel imidazolidine derivatives as candidates to schistosomicidal agents
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Synthesis and biological evaluation of novel imidazolidine derivatives as candidates to schistosomicidal agents
Introduction: Schistosomiasis is an infectious parasitic disease caused by trematodes of the genus Schistosoma, which threatens at least 258 million people worldwide and its control is dependent on a single drug, praziquantel. The aim of this study was to evaluate the anti-Schistosoma mansoni activity in vitro of novel imidazolidine derivatives. Material and methods: We synthesized two novel...
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ژورنال
عنوان ژورنال: Revista do Instituto de Medicina Tropical de São Paulo
سال: 2017
ISSN: 0036-4665
DOI: 10.1590/s1678-9946201759008